Res clearance in humans
Advances in Imaging the Glymphatic System
The glymphatic system is a brain-wide fluid transport mechanism that facilitates cerebrospinal fluid and interstitial fluid exchange, playing a crucial role in waste clearance. Dysfunction of this system has been implicated in
Back to the Physiology: Renal Tubular Handling of Uric Acid
Hyperuricemia is a common comorbidity of chronic kidney disease (CKD) and contributes to kidney dysfunction through mechanisms involving glomerular, tubular, and vascular injuries.
Diagnostic evaluation of the kidney and urinary
A precise evaluation of creatinine clearance requires measuring creatinine in the urine over a 24-hour period. Creatinine clearance can be used to approximate the GFR. Several prediction equations can be used in clinical
Approaching kidney failure
Kidney treatments and care provided on the NHS is also closely monitored by the UK Renal Registry which uses data to improve the lives of people with kidney disease. Ask your kidney doctor to explain all the treatment
Nanotechnology and cell death: Revolutionizing disease
The application of nanotechnology in medicine has expanded significantly in recent years, with nanoparticles (NPs) emerging as promising drug carriers for disease treatment. This review
Radiation dosimetry and fasting-dependent hepatobiliary clearance
Determining its bio-distribution and dose exposure in humans is essential for clinical implementation, particularly given hepatobiliary clearance observed in pre-clinical models.
An all-in-one pipeline for the in vitro discovery and in vivo
Using whole animal bioluminescence imaging, we assess the in vivo gametocyte killing and clearance kinetics of antimalarial reference drugs and clinical drug candidates and identify
Computer Science Fully Funded PhD Studentship In
This scholarship covers the full cost of tuition and annual stipend at standard UKRI rates (currently £20,780 for 2025/26). Additional research expenses of up to £1,000 per year will
Lipoprotein (a): A new target for pharmacological research
Lipoprotein (a) [Lp (a)] is increasingly recognised as a crucial and independent risk factor for atherosclerotic cardiovascular disease (ASCVD), calcific aortic valve stenosis (AVS), and
Institutional Human Ethics Committee (IHEC)
Background As per the Goa University Guidelines for Academic Ethics, experiments involving cell lines, stem cell research and human subjects come under the purview of the University Institutional Human Ethics
Long-term exercise enhances meningeal lymphatic vessel
Background Meningeal lymphatic drainage is crucial for the clearance of amyloid β (Aβ), supporting the maintenance of brain homeostasis. This makes it a promising therapeutic target
770,000 years ago, early humans in Spain ate children | The
Jerusalem Post / Archaeology New evidence in Spain: 770,000 years ago, early humans ate children Palmira Saladié : "The vertebra shows sharp incisions at important anatomical points
Nicotinamide N-Methyltransferase in Non-Alcoholic Fatty
Further research is needed to confirm these effects in larger sample sizes and in humans. Liver sinusoidal endothelial cells (LSECs) represent a highly specialized endothelial subtype
Alzheimer''s & Dementia: Translational Research
Intranasal [68 Ga]Ga-NOTA-insulin is a safe and effective positron emission tomography radiotracer in humans. Intranasal insulin increased brain uptake in multiple regions for all participants. Uptake varied by cognitive status, sex,
Advances in Liposomal Drug Delivery: Multidirectional
Liposomes represent a cornerstone of modern drug delivery systems due to their unique structural and physicochemical characteristics. Extensive research has refined their formulation, stability,
